500 home runs: percent at home. Mel Ott tops. Albert Pujols bottom.

HR≥500 for career, sorted by greatest percentage of total Home Runs at home:

Rk	I	Player	Split	From	To	G	HR	HRtot	%	GS	PA	AB	R	H	2B	3B	RBI	SB	CS	BB	SO	BA	OBP	SLG	OPS	TB	GDP	HBP	SH	SF	IBB	ROE	BAbip
1		Mel Ott	Home	1926	1947	1367	323	511	63.2	1282	5600	4576	954	1360	182	21	947	49	3	955	429	.297	.422	.558	.980	2553	36	31	38	0	12	10	.271
2		Frank Thomas	Home	1990	2008	1173	312	521	59.9	1160	5011	4083	810	1246	250	7	889	15	13	840	685	.305	.424	.599	1.024	2446	115	41	0	47	84	31	.298
3		Ernie Banks	Home	1953	1971	1285	290	512	56.6	1251	5258	4734	722	1372	218	42	909	22	24	417	564	.290	.348	.537	.886	2544	124	35	23	49	106	77	.275
4		Jimmie Foxx	Home	1925	1945	1145	299	534	56.0	1050	4678	3885	930	1341	220	58	1029	44	34	760	615	.345	.453	.663	1.116	2574	34	9	24	0	6	7	.351
5		Jim Thome	Home	1991	2012	1287	339	612	55.4	1216	5165	4189	836	1157	222	15	921	13	8	900	1230	.276	.406	.579	.985	2426	80	40	1	35	91	33	.308
6		Frank Robinson	Home	1956	1976	1383	321	586	54.8	1310	5649	4779	958	1462	255	28	970	91	34	708	709	.306	.403	.573	.975	2736	131	101	7	54	122	80	.300
7		Rafael Palmeiro	Home	1986	2005	1424	311	569	54.7	1371	5981	5135	866	1466	265	22	935	47	19	736	702	.285	.375	.527	.903	2708	123	40	10	60	98	43	.276
8		Sammy Sosa	Home	1989	2007	1184	321	609	52.7	1140	4897	4333	738	1199	188	27	853	109	54	490	1098	.277	.350	.555	.905	2404	102	24	7	43	83	56	.297
9		Ken Griffey	Home	1989	2010	1319	332	630	52.7	1261	5508	4732	859	1400	283	16	962	96	28	675	806	.296	.385	.573	.958	2711	87	44	5	52	113	39	.293
10		Gary Sheffield	Home	1988	2009	1294	262	509	51.5	1262	5409	4515	839	1337	228	14	841	115	47	762	552	.296	.402	.527	.929	2379	108	74	5	53	66	52	.286
11		Alex Rodriguez	Home	1994	2013	1287	334	654	51.1	1274	5576	4833	972	1481	269	13	1009	173	30	600	1017	.306	.389	.575	.964	2778	129	86	7	50	45	65	.325
12		Hank Aaron	Home	1954	1976	1647	385	755	51.0	1590	6804	5968	1081	1811	283	37	1117	117	32	746	651	.303	.379	.557	.936	3323	133	17	15	58	159	90	.286
13		Manny Ramirez	Home	1993	2011	1151	282	555	50.8	1119	4790	4016	778	1247	258	11	947	16	19	670	897	.311	.413	.591	1.003	2373	124	59	1	44	127	34	.335
14		Harmon Killebrew	Home	1954	1975	1203	291	573	50.8	1118	4764	3935	642	1018	137	8	827	12	10	769	796	.259	.379	.519	.899	2044	114	20	0	40	92	71	.252
15		Willie Mays	Home	1951	1973	1490	335	660	50.8	1400	6027	5238	1017	1583	258	61	929	145	47	721	659	.302	.387	.567	.953	2968	121	23	9	36	101	86	.292
16		Willie McCovey	Home	1959	1980	1262	264	521	50.7	1107	4625	3907	609	1057	171	19	774	11	9	654	724	.271	.377	.527	.904	2058	77	30	3	27	138	56	.269
17		Barry Bonds	Home	1986	2007	1492	379	762	49.7	1415	6124	4757	1105	1430	292	40	980	259	62	1256	754	.301	.449	.618	1.067	2939	79	60	4	47	340	38	.286
18		Reggie Jackson	Home	1967	1987	1410	280	563	49.7	1318	5546	4799	730	1226	196	23	826	99	50	663	1305	.255	.349	.481	.830	2308	82	46	7	31	82	54	.292
19		Mickey Mantle	Home	1951	1968	1213	266	536	49.6	1153	4878	3970	825	1211	163	44	744	74	19	869	808	.305	.428	.569	.997	2260	56	4	6	29	79	57	.323
20		Mark McGwire	Home	1986	2001	934	285	583	48.9	893	3777	3009	573	789	127	3	701	5	3	686	772	.262	.402	.591	.993	1777	82	43	1	38	88	33	.253
21		Babe Ruth	Home	1914	1935	1253	347	714	48.6	1201	5150	4035	1078	1398	239	70	1062	72	68	1044	615	.346	.483	.698	1.181	2818	0	18	53	0		0	.342
22		Mike Schmidt	Home	1972	1989	1202	265	548	48.4	1155	4922	4020	784	1094	220	31	825	82	45	788	897	.272	.393	.540	.933	2171	84	48	6	60	104	54	.284
23		Eddie Murray	Home	1977	1997	1517	242	504	48.0	1490	6277	5532	802	1595	244	17	934	61	25	676	740	.288	.364	.470	.833	2599	168	10	2	57	118	75	.294
24		Ted Williams	Home	1939	1960	1165	248	521	47.6	1094	4954	3887	974	1403	319	35	965	18	8	1031	323	.361	.496	.652	1.148	2536	97	22	3	11	106	33	.347
25		Eddie Mathews	Home	1952	1968	1179	238	512	46.5	1128	4830	4088	698	1081	158	21	666	41	19	686	726	.264	.370	.488	.858	1995	64	12	18	26	67	47	.268
Rk	I	Player	Split	From	To	G	HR	HRtot	%	GS	PA	AB	R	H	2B	3B	RBI	SB	CS	BB	SO	BA	OBP	SLG	OPS	TB	GDP	HBP	SH	SF	IBB	ROE	BAbip
26		Albert Pujols	Home	2001	2014	1063	239	520	46.0	1041	4533	3868	722	1245	299	4	810	51	21	572	413	.322	.412	.587	.998	2269	143	48	1	44	131	37	.309

Provided by Baseball-Reference.com: View Play Index Tool Used
Generated 1/5/2015.

1940 Bowman Gum via Wikimedia Commons

Mel Ott is the only 500 home run (HR) hitter with more than 60% at home: 63.2%.  Hank Aaron hit the most HR at home: 385 (51%).  Aaron's teammate Eddie Mathews hit the fewest at home: 238 (46.5%).  16 of the 26 hit at least 50% at home.  The ten with less than 50% at home includes:
Barry Bonds 49.7%
Mickey Mantle 49.6%
Babe Ruth 48.6%

Five had at least 55% at home:
Ott 63.2%
Thomas 59.9%
Banks 56.6%
Foxx 56%
Thome 55.4%

Mel Ott played his entire career for the New York Giants: 1926-1947.  In 1943 Ott hit 18 HR, all at home.

I	Split	G	GS	PA	AB	R	H	2B	3B	HR	RBI	SB	CS	BB	SO	BA	OBP	SLG	OPS	TB	GDP	HBP	SH	SF	IBB	ROE	BAbip	tOPS+	sOPS+
	Home	65	62	272	211	41	50	6	0	18	35	4	0	59	26	.237	.406	.521	.927	110	1	1	1	0	1	0	.192	127	170
	Away	60	49	213	169	24	39	6	2	0	13	3	0	40	22	.231	.384	.290	.674	49	3	2	2	0	0	2	.265	66	108

Ott led the National League in HR six times:
1932 38
1934 35
1936 33
1937 31
1938 36
1942 30

His highest total was in 1929: 42, the only time he reached 40.  Oddly, Ott hit more on the road than at home in 1929:

I	Split	G	GS	PA	AB	R	H	2B	3B	HR	RBI	SB	CS	BB	SO	BA	OBP	SLG	OPS	TB	GDP	HBP	SH	SF	IBB	ROE	BAbip	tOPS+	sOPS+
	Home	75	74	325	266	59	79	12	1	20	65	3	0	54	17	.297	.417	.575	.993	153		1	4	0			.258	83	150
	Away	75	75	350	279	79	100	25	1	22	87	3	0	59	21	.358	.478	.692	1.170	193		5	7	0			.331	115	208

Ott Career:
Home: 323 HR in 4,576 AB
Road: 188 HR in 4,879 AB

Mel Ott:
Positions: Rightfielder and Third Baseman
Bats: Left, Throws: Right
Height: 5' 9", Weight: 170 lb.

Born: March 2, 1909 in Gretna, LA
Died: November 21, 1958 in New Orleans, LA (Aged 49.264)