Ty Cobb played five Negro League games.

The Baseball Reference page for Ty Cobb contains an link for "Negro Leagues":


http://www.baseball-reference.com/nlb/player.cgi?id=cobb--001tyr

Year	Age	AgeDif	Tm	Lg	Lev	G	PA	AB	R	H	2B	3B	HR	RBI	SB	CS	BB	SO	BA	OBP	SLG	OPS	TB	GDP	HBP	SH	SF	IBB
1910	23		Detroit	CMLS	Fgn	5	23	20	4	7	0	1	1	5	0	1	2	1	.350	.391	.600	.991	12			0	1
1 Season						5	23	20	4	7	0	1	1	5	0	1	2	1	.350	.391	.600	.991	12			0	1

Provided by Baseball-Reference.com: View Original Table
Generated 6/9/2015.

1910 Cuban-American Major League Clubs Series

Regular Season

Tm W L W-L% GB Philadelphia Athletics Habana Detroit Tigers Almendares

Cuban-American Major League Clubs Series (Foreign) Encyclopedia and History

Year	Tm
1913	Almendares, Brooklyn Dodgers, Habana
1912	Almendares, Habana, Philadelphia Athletics
1911	Almendares Park, Havana Park, New York Giants, Philadelphia Phillies
1910	Almendares, Detroit Tigers, Habana, Philadelphia Athletics
1909	All-Stars, Almendares, Detroit Tigers, Habana
1908	Almendares, Brooklyn Royal Giants, Cincinnati Reds, Habana

Provided by Baseball-Reference.com: View Original Table
Generated 6/9/2015.

American Series

1909 ... Detroit, the American League pennant winner, went 4–8.  Detroit star Ty Cobb did not participate in the series.

1910 ... the Detroit Tigers went 7-4 in 12 games.
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I'm finally getting around to reading:

"Ty Cobb: A Terrible Beauty". New book challenges view of Cobb as racist. Monday, May 25, 2015